Life Extension, Super K With Advanced K2 Complex, 90 Softgels
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Life Extension, Super K With Advanced K2 Complex, 90 Softgels
Expiration Date:Expiration Date
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Shipping Weight:0.18 lbsSwitch to Metric units
- Product Code: LEX-18349
- UPC Code: 737870183495
- Package Quantity: 90 Softgel
1.8 x 1.8 x 3.4 in, 0.15 lbsSwitch to Metric units
- Promoted Arterial Health and Healthy Bones
- Dietary Supplement
An abundance of human clinical data reveals that vitamin K plays a critical role in maintaining healthy bone density by facilitating the transport of calcium from the bloodstream into the bone. Vitamin K is also required by calcium-regulating proteins in the arteries. Matrix Gla-protein (MGP) is a vitamin K-dependent protein, and it must be carboxylated to function properly. Poor vitamin K status leads to inactive uncarboxylated MGP (ucMGP), which accumulates at sites of arterial calcification. Since MGP is a potent local inhibitor of arterial calcification, MGP is important in relation to the health of the entire cardiovascular system. Without adequate vitamin K, calcium in the blood can bind to the arterial wall resulting in calcification. As people age, even a subclinical vitamin K deficiency can pose risks to the vascular system. Poor vitamin K status also results in increased circulating levels of undercarboxylated osteocalcin that is shown to be associated with increased bone loss in postmenopausal women.
Humans get most of their vitamin K from green vegetables in the form of vitamin K1. The problem is that K1 is tightly bound to plant fiber and only a small fraction absorbs into the bloodstream.
Vitamin K2 (menaquinones) is found in meat, eggs, and dairy products and is also made by bacteria in the human gut, which provides a certain amount of the human vitamin K requirement. Human studies show that vitamin K2 is up to ten times more bioavailable than K1. Vitamin K2 remains biologically active in the body far longer than K1. For instance, K1 is rapidly cleared by the liver within eight hours, whereas measurable levels of K2 (MK-7) have been detected 72 hours after ingestion.
The Rotterdam Heart Study, a large-scale, well-controlled clinical trial that tracked 4,800 participants for seven years, revealed that participants who ingested the greatest quantities of vitamin K2 in their diet experienced a better cardiovascular condition than people who ingested the least. High intakes of vitamin K2 also corresponded to less calcium deposition in the aorta, whereas participants who ingested less K2 were more likely to show moderate or severe calcification. Animal studies suggest vitamin K intake not only blocks the progress of further calcium accumulation, but also induces 37% regression of preformed arterial calcification.
Ideal Forms of Vitamin K2
In recent years, two forms of vitamin K2 have been extensively researched and the findings reveal vastly improved effects compared to K1. The MK-4 form of vitamin K2 is the most rapidly absorbed and is now routinely used in Japan to maintain healthy bone density. MK-4, however, only remains active in the blood for a few hours. The MK-7 form of K2, on the other hand, remains bioavailable to the human body over a sustained 24-hour period and to higher levels (seven- to eightfold) during prolonged intake. Both MK-4 and MK-7 have demonstrated remarkable health benefits when studied in human populations.
The Most Complete Vitamin K Formula
Vitamin K1 is the form found in plants and vegetables and should be part of most people’s daily supplement regimen. Even more important is inclusion of the MK-4 and MK-7 forms of vitamin K2.
Based on data substantiating the long-acting effects of MK-7, it is now possible to ingest fewer total micrograms of vitamin K but achieve far higher sustained blood levels of this critical nutrient.
The latest Super K with Advanced K2 Complex formula provides vitamin K1 and the MK-4 and MK-7 forms of vitamin K2 in just one daily softgel. The virtue of this formula is that it provides the precise amount of the long-acting MK-7 form of vitamin K2 that recent human studies have shown provides optimal K2 levels over a 24-hour period. The MK-4 is included to provide the rapid increase in vitamin K blood levels that may account for its beneficial effects in certain studies.
Read the entire label and follow the directions carefully prior to use.
Take one (1) softgel daily with food, or as recommended by a healthcare practitioner.
Extra virgin olive oil, gelatin, glycerin, beeswax, purified water, carob color.
Caution: If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult with your healthcare provider before taking this product.
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Store tightly closed in a cool, dry place.
|Serving Size: 1 Softgel|
|Amount Per Serving||%Daily Value|
|Vitamin C (as Ascorbyl palmitate)||10 mg||17%|
|Vitamin K activity from:||2700 mcg||3375%|
|Vitamin K1 (as phytonadione)||1500 mcg|
|Vitamin K2 (as menaquinone-4)||1000 mcg|
|Vitamin K2 (as menaquinone-7)||200 mcg|
review of a product
review of a product
I ordered this because I'm taking high doses of vitamin D and this product is highly recommended to be taken alongside vitamin D to avoid calcium loss from the bones - at least untill I get into shape and be able to run or briskly walk for half an hour a day. Actually I'll know when I do a DXA scan of the bones in about a year from now, because currently I have osteopenia... regards, Jaka
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Very good with D3
Posted by iHerb Customer on Jan 24, 2018 | Verified Purchase
I recommend this product for everyone who takes Wit D3 in high amounts. It helps to absorb Wit to body, and also helps to reduce calcium from blood. It's very importand to prevent calcification of veins. VERY GOOD!
Recommended by Ruska Myrsky
Posted by RuskaMyrsky on Dec 25, 2017 | Verified Purchase
The most beneficial Vitamin K vitamins are K2 MK7 and K2 MK4. This contains them. K1 is not that beneficial and you get enought of it if you eat a lot of greens. K2 is made by bacteria for example in some cheeses. You can not get optimal amounts of K2 from food alone unless you eat huge amounts of Japanese Natto.
Posted by iHerb Customer on Dec 21, 2017 | Verified Purchase
I highly recommend this product for people who use high amounts of vitamin D3 daily, like 5,000 to 10,000 iu's or people with poor cholesterol levels. Vitamin K2 is a supplement that prevents plaque build-up in arteries and even reverse it to some degree. Very good for people with low HDL levels.
Posted by iHerb Customer on Nov 28, 2017 | Verified Purchase
Been recommended to me and hopefully does what it is meant to do in combination with vitamin d3.
Taking with Calcium for better bones.
Posted by iHerb Customer on Nov 18, 2017 | Verified Purchase
I take it with calcium and D3.