This is a phenomenal probiotic product that completely eliminated clostridia from my husband's gut - verified via tests. However, be aware that SOME people are severely allergic to the lactobacillus bacteria strain. My mother developed an allergic reaction when taking this product which included bladder and kidney problems and severe rash on her arms. Nowhere is this possible reaction noted on the product. This went on for weeks until we did more research. We had to do several searches on the internet and came across this finding. Within 48 hours of stopping culturelle, her symptoms abated. Scary. Just beware.